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ImClone Systems And Bristol-Myers Squibb Announce Revisions To ERBITUX(R) (cetuximab) U.S. Product Labeling For Metastatic Colorectal Cancer
ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company (NYSE: LLY), and Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has approved revisions to the U.S. prescribing information for ERBITUX® (cetuximab) concerning the treatment of patients with epidermal growth factor receptor (EGFR)-expressing metastatic colorectal cancer (mCRC). The labeling revisions include a modification to the indication, which now includes a statement that retrospective subset analyses of metastatic or advanced colorectal cancer trials have not shown a treatment benefit for ERBITUX in patients whose tumors had K-ras mutations in codon 12 or 13 and that the use of ERBITUX is not recommended for the treatment of colorectal cancer with these mutations. Revisions concerning the use of ERBITUX in colorectal cancer tumors with K-ras mutations were also made to the clinical studies and clinical pharmacology sections of the product"s prescribing information.
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Myelin Removal Beads: Premium Efficiency For Neural Cell Separations And Antibody Stainings
Miltenyi Biotec announces the worldwide and exclusive release of Myelin Removal Beads. Myelin is a specialized membrane which ensheathes and insulates axons in the peripheral and central nervous system. During preparation of single-cell suspensions, myelin membrane fragments represent the major contaminant. "When dissociating adult neural tissue, usually less than 5 percent of the cell suspension consists of cells. The rest corresponds to cell debris", explains Dr. Rebecca Biloune, Product Manager for Neural Research Products at Miltenyi Biotec. "Removal of myelin leads to higher purity and recovery of target cells."
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New Book About Women's Health Looks At The Good And Evil Of Hormones
The evidence is in. Estrogen does not halt aging or protect women from heart disease and dementia, nor is it the safest or best treatment for the hot flashes, night sweats and the insomnia that are associated with menopause and perimenopause. Quite simply - estrogen is not a good and magical hormone - as Susan Baxter, PhD., and Dr. Jerilynn C. Prior, painstakingly prove in their book, The Estrogen Errors; Why Progesterone is Better for Women"s Health.
Nutrition

Case Study: Paying For Health Care In A Recession

NPR reports on the health care struggles of Howard County, Maryland, a well-off and generally liberal area with hospital fees set by the state and a county program for the uninsured. "But like the rest the country, Howard County is facing the impact of the recession: Employers have to cut back on benefits, so employees cut back on their coverage." Herb Huston, 61, lost his employer-provided insurance when he was laid off a few years ago. He"d always been healthy, but one night in May he suffered a heart attack. "Neither old enough for Medicare nor poor enough for Medicaid," Huston will be responsible for the costs himself, which "should easily exceed $50,000." On the other end of the spectrum is 62-year-old Judy Weeter, who pays no premium for the insurance she receives through her employer. She"s undergoing expensive chemotherapy for breast cancer but expects to pay no more than her $20 copays. But Linda Faggio, who "administers the oncology practice where Weeter gets chemo" says she is "seeing an increasing number of patients who are underinsured and can"t afford adequate coverage." Many have "reduced their coverage because their employers have reduced their contributions" as sales slumped in the recession. Lin Eagan, who runs a mortgage company that employs 15 people, "went from paying 100 percent of her employees" health insurance to a 50-50 split" after the residential real estate market crashed. "Obviously we needed to look at cuts in the payroll. In our whole budget, health care was a big number," she explains. "Small businesses like Eagan"s have been making similar decisions in Howard County and all over the country. Workers who are laid off get COBRA and without a new job could end up uninsured. But workers who keep their jobs face steeply increased premiums as the burden shifts to them, and they take cheaper options and risk being underinsured" (Siegel, 6/15). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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