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Loan Repayment Legislation Includes Physical Therapists As Frontline Providers
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Focusing On The More Lethal Form Of The Cancer Rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is an aggressive muscle cancer that mostly affects children. The most common forms of RMS are embryonal rhabdomyosarcoma (ERMS) and alveolar rhabdomyosarcoma (ARMS). Although ARMS is less common than ERMS, it is associated with a much higher rate of mortality. A therapy tailored to the ARMS form of RMS is therefore badly needed. A team of researchers, at the Hospital for Sick Children, Toronto, and Monash Institute of Medical Research, Australia, has now provided hope that it might be possible to develop such a therapy by showing that the protein ILK promotes the growth of ARMS cells, whereas it suppresses the growth of ERMS cells.
Sexual Health

Child's Body Composition May Be Shaped By Breastfeeding Duration And Weaning Diet

Variations in both milk feeding and in the weaning diet are linked to differences in growth and development, and they have independent influences on body composition in early childhood, according to a new study accepted for publication in The Endocrine Society"s Journal of Clinical Endocrinology & Metabolism (JCEM). Previous studies suggest that the early environment may be a significant factor in childhood obesity. This study used dual x-ray absorptiometry to make direct measures of body composition in children at four years of age whose diets had been assessed when they were infants. The findings showed that children who had been breastfed longer had a lower fat mass which could not be explained by differences in family background or the child"s height. "Most studies linking infant feeding to later body composition focus on differences in milk feeding, but our study also considered the influence of the weaning diet," said Dr. SiÃþn Robinson, PhD, of the MRC Epidemiology Re Centre, University of Southampton in the United Kingdom and lead author of the study. "We found that, independent of the duration of breastfeeding, children with higher quality weaning diets including fruits, vegetables, and home-prepared foods had a greater lean mass at four years of age." In this study, researchers assessed the diets of 536 children at six and 12 months of age. Diet was assessed using a food frequency questionnaire that was administered by trained research nurses to record the average frequency of consumption of specific foods. The age at which solid foods were introduced into the infant"s diet was also recorded. In this study "weaning" is defined as the period of transition in infancy between a diet based on milk feeding to one based on solid foods. The subjects" body composition was assessed at four years by dual X-ray absorptiometry. "These findings are enlightening," said Professor Cyrus Cooper, Director of the MRC Epidemiology Re Centre. "An influence of qualitative differences in the weaning diet on childhood body composition had not been described before." Other researchers working on the study include Lynne Marriott, Sarah Crozier, Nick Harvey, Catharine Gale, Hazel Inskip, Janis Baird, Keith Godfrey, and Cyrus Cooper of the University of Southampton in the United Kingdom and Catherine Law of University College London in the United Kingdom. The study was funded by the UK Medical Research Council, University of Southampton, British Heart Foundation and the Food Standards Agency. The article "Variations in infant feeding practice are associated with body composition in childhood: a prospective cohort study," will appear in the August 2009 issue of JCEM. Aaron Lohr The Endocrine Society


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