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Inhaled Growth Hormone Safe For Children Deficient In This Key Protein
A multi-center clinical trial led by a Riley Hospital for Children endocrinologist has found that inhaled growth hormone (GH) is well tolerated by children with GH deficiency and that this easy-to-use method can, over a one-week period, safely deliver GH to the blood stream. In addition to having implications for those who need GH, this first pediatric study of administering it through the lungs may also help researchers interested in using this convenient method for effectively delivering other types of medications to children.
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Landmark Five-Year African Study Indicates That HIV Therapy May Be Given Safely In Re-Limited Settings Without Routine Laboratory Monitoring
Gilead Sciences, Inc. (Nasdaq:GILD) highlighted results from a study known as DART (Development of Anti-Retroviral Treatment in Africa), which evaluated the need for routine laboratory monitoring in adults taking antiretroviral therapy in Africa. The DART trial was an open-label, randomized study comparing clinical and laboratory monitoring to clinical monitoring alone for efficacy and toxicity. In this study, 74 percent of patients were on a treatment regimen containing Viread® (tenofovir disoproxil fumarate). At baseline, more than 50 percent of patients had reduced renal function. The results indicated that Viread was well tolerated and that the incidence of renal adverse events was low. DART researchers concluded that renal function test results were similar in both arms of the trial for up to five years, suggesting that routine monitoring of Viread may not be necessary in re-limited settings when using the product as part of a first-line HIV treatment regimen. The results of the study were presented today at the 5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2009) in Cape Town, South Africa.
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Nurses Welcome News That Infection Rates Are Decreasing
Welcoming the publication of the National Audit Office report, Reducing Healthcare Associated Infections in Hospitals in England, Dr Peter Carter, RCN Chief Executive & General Secretary, said:
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Endocrine Society Unveils First-Ever Scientific Statement

Endocrine Society Unveils First-Ever Scientific Statement: Inaugural Statement Identifies Endocrine-Disrupting Chemicals as a Significant Concern to Public Health The Endocrine Society presented its first-ever Scientific Statement on endocrine-disrupting chemicals today at ENDO 09, the 91st Annual Meeting of The Endocrine Society. The Scientific Statement presents evidence on the health effects of endocrine-disrupting chemicals as well as recommendations for increasing understanding and raising awareness of these effects. Endocrine-disrupting chemicals are substances in the environment that interfere with hormone biosynthesis, metabolism or action resulting in adverse developmental, reproductive, neurological and immune effects in both humans and wildlife. "From chemicals in pesticides, food, plastic bottles and other items that we use every day, the concern is real," said Robert M. Carey, MD, president of The Endocrine Society. "In this Scientific Statement on endocrine-disrupting chemicals- developed by a group of experts in the field-we present evidence that shows endocrine disruptors have effects on male and female reproduction, breast development and cancer, prostate cancer, neuroendocrinology, thyroid disease, metabolism and obesity, and cardiovascular endocrinology." The Scientific Statement is a brand new initiative of The Endocrine Society. The statements are designed to educate basic scientists, clinical scientists, and clinicians about the scientific evidence for the basis of disease. This evidence can also be applied in the practice of medicine with regard to both prevention and management. "Within this statement we also make a number of recommendations to increase understanding of the effects of endocrine disruptors," said Dr. Carey. "The recommendations include enhancing basic and clinical research, and advocating involvement of individual and scientific society stakeholders in communicating and implementing changes in public policy and awareness." The Endocrine Society


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