Oncology
An initial version of health reform legislation could be available "in the next several days," Sen. Chris Dodd, D-Conn., a senior member of the Senate Health, Education, Labor and Pensions Committee, told Dow Jones Newswires. Dodd added that another Democrat had presented ""four or five" different versions of a public plan Wednesday," but that the committee had not yet ironed out those controversial details (Yoest, 6/3).
Abbott (NYSE: ABT) and AstraZeneca announced that the companies have submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for an investigational compound for the treatment of mixed dyslipidemia, a combination of two or more lipid abnormalities including high LDL- cholesterol (the "bad" cholesterol), high triglycerides and low HDL-cholesterol (the "good" cholesterol). The NDA submission for this investigational compound, containing the active ingredients of CRESTOR(R) (rosuvastatin calcium) and TRILIPIX(R) (fenofibric acid), is supported by data from multiple studies, including efficacy and safety studies with the 5mg, 10mg and 20mg doses of rosuvastatin combined with fenofibric acid. Pending approval of the NDA, the treatment will be marketed as CERTRIAD(TM).
Tamiflu
During the warmer months, the use of trampolines is more frequent and as a result children are more likely to be hospitalized with related injuries, especially after bouncing with adults at the same time, according to doctors" warnings.
Whether and how medical personnel and their digital systems can talk to one another in a meaningful way is a subject pertinent to the health of patients about whom they "converse."
TCT Symposium will feature strategies for nurses and technologists to improve care for angioplasty patients
More than 80 community pharmacists from the National Community Pharmacists Association (NCPA) and several patients met with the Federal Trade Commission (FTC) today to discuss the negative impact of the March 2007 CVS/Caremark merger and to urge the FTC to re-examine it.
"Flying into a developing country, operating on people for a few days or weeks and flying out again helps individual persons but has nothing to do with sustainable development work." Professor Martin Salzer, Vice-president of "Austrian Doctors for Disabled" -- the Austrian society for medical development assistance -- is convinced that "it makes even less sense to fly in people from such countries for difficult operations, as humanitarian the motive may be. That money can be invested more effectively." For the group of physicians and medically interested persons around Prof. Salzer it is a question of sustainability in the field of development cooperation, something to which they can contribute their medical experience. "After care for the disability or sickness, our concern is networked interdisciplinary and sustainable rehabilitation. We also hope to thereby make a contribution toward combating poverty" Prof. Salzer says in summing up the main concern of the organization.
Dr. Eric Olson, chairman of molecular biology at UT Southwestern Medical Center, has been awarded the Institut de France"s prestigious Lefoulon-Delalande Foundation Grand Prize for his work on gene regulation in the cardiovascular system.
Huge economic gains could be made if eyeglasses were provided to approximately 150 million people in need, according to research published today in the international public health journal, the Bulletin of the World Health Organization.
New standards to improve access to diagnosis and treatment of sarcomas have been published by the Welsh Assembly Government.
The health service is entering a "dark and dangerous period" because of the economic crisis, the Chairman of the BMA"s Consultants Committee warned in a speech. Arguing that public money must not be diverted away from patient care into "the pockets of shareholders", Dr Jonathan Fielden called for private management consultants to be "ditched" from the NHS.
Journalist, Malini Guha, has won the prestigious new Advances in Renal Cancer Journalists" Award - Europe for her article "New Advances Deliver Fresh Hope in Kidney Cancer" - which was published in Scrip World Pharmaceutical News on February 13th 2009.
Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a range of other disorders. Acting like an "on-off switch," the medications might ratchet up the production of proteins in genes working at abnormally low levels or shut off genes producing an abnormal protein linked to disease. Their report is in the current issue of ACS Chemical Biology, a monthly journal.
Less than a quarter of psychiatric research papers published in medical journals have a female first author, according to new research presented at the Royal College of Psychiatrists" 2009 Annual Meeting.
A well-crafted case study is a powerful educational and marketing tool. The Pharmacy Benefit Management Institute"s (PBMI) 15th Anniversary Drug Benefit Conference offers industry experts an opportunity to present case studies that showcase solutions to critical drug benefit challenges. Speaker proposals will be accepted until August 14, 2009 for the conference to be held February 17-19, 2010 in Phoenix.
InfoMedics, Inc., the patient feedback company, recently co-authored two posters detailing patients" experiences with the attention-deficit/hyperactivity disorder (ADHD) drug lisdexamfetamine dimesylate (LDX).
Shortly after the American Recovery and Reinvestment Act passed in February, there was a government affairs retreat of the eHealth Initiative to discuss concern regarding the $19 billion allocated for health information technology. A feature article in the June issue of the Journal of AHIMA examines conclusions policy makers made about the investment in health IT and how to engage healthcare consumers in productive use of it.
Clinical trial results presented today at the American Diabetes Association annual meeting show that overall rates of cardiovascular hospitalization and cardiovascular death are similar in patients taking Avandia (rosiglitazone) compared to those receiving metformin and sulfonylurea.
Can a patient be awake and communicating with the anesthesiologist and surgeon during general anesthesia? With a new "cooperative patient" anesthesia technique, the answer is yes, according to a study in the June issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).
The following summarizes selected women"s health-related blog entries.~ "Dr. Tiller -- A Gynecological Superhero," Frances Irwin, Below the Waist: Kansas abortion provider George Tiller, who was shot to death on Sunday, was "a superhero" who "never failed to serve his patients regardless of the level of property damage, physical injury and intimidation he was subjected to as a result of his service," Irwin, who works for a Wisconsin-based family planning agency, writes. Irwin notes that, for nearly a year, the clinic she works at has been targeted by "pro-life" demonstrators. At various points they"ve carried signs reading, "Family planners promote child promiscuity," "Stop ALL Abortion," "Birth Control Leads to Abortion," and that new signs mention her by name. In the wake of Tiller"s death, Irwin writes that she "realize[s] that I could be intentionally injured by someone who opposes my work." She concludes, "To some extent allowing myself to worry about this feels like cowardice because Dr. Tiller was a superhero. And that"s a lot to aspire to" (Irwin, Below the Waist, 6/4).~ "Let"s Make an Abortion Deal," William Saletan, Slate"s "Human Nature": Some participants in the White House meetings to discuss abortion in the U.S. "aren"t trying hard enough" to find "common ground" and are "refusing the simplest concessions," Saletan writes. Saletan offers four recommendations to advocates on both side of the debate, including removing the distinction between reducing the number of abortions versus reducing the need for abortions. He writes, "No ordinary person sees a difference" between the two,"[s]o let"s focus on reduction through voluntary means and stop quibbling over how it"s described." His other recommendations include antiabortion-rights advocates conceding to increased access to contraception and both sides giving up "extremism." Saletan"s final recommendation is that abortion-rights opponents allow federal funding for reproductive health groups that offer abortion information or services. He writes that a ban on direct funding for abortions is "fine, " but the "indirect funding Obama restored is hardly radical," adding, "You might even discover that the most efficient way to prevent abortions in the long term is to fund the family planning organizations you keep trying to defund" (Saletan, "Human Nature," Slate, 6/4).~ "The ABCs of Antiabortion Activism," Tracy Clark-Flory, Salon"s "Broadsheet": Tiller"s murder "has opened up a Pandora"s box for pro-lifers, giving rise to all sorts of troublesome questions about the culpability of lenient law enforcement and the movement itself," Clark-Flory writes. She continues, "They certainly won"t find salvation from Pandagon"s Amanda Marcotte, who got her mitts on a disturbing antiabortion activist handbook" now online from Justice for All "that lays bare some of the lies, deception and cynical manipulation that might have led to Tiller"s assassination." According to Clark-Flory, "The single justifiable situation for an abortion is ectopic pregnancy, the manual explains," adding, "Deception of that sort is found throughout the handbook." She writes, "Activists are instructed that when confronting targets they are to pretend that they"re A-OK with contraception" so that "their mark will let his or her guard down and think that, you know, there"s actually a rational, fact-based discussion to be had." Clark-Flory continues, "The truth, of course, is that the manual goes on to arm activists with medical misinformation that they can spread about birth control." She concludes that Marcotte "puts this tactical deceit in perfect context: "It shows one face to the initiated and another to the public, especially on the topic of contraception. Once you realize this, the movement"s half-hearted denunciations of Dr. Tiller"s murder, coupled with the enthusiastic return to calling Dr. Tiller a monster, become all the more chilling"" (Clark-Flory, "Broadsheet," Salon, 6/4).~ "Late-Term Abortions: Facts
A new two-year trial to test a tuberculosis vaccine aimed at boosting the efficacy of the BCG vaccine is scheduled to begin soon in South Africa, IRIN reports (IRIN, 6/4). The vaccine candidate, called MVA85A, will be tested next month in 2,874 children younger than age one. The new tests will be the "first concept trial of a new preventative TB vaccine for infants in close to 90 years," according to Reuters.
HIV Specialty Clinics Across U.S. Closing, Changing Focus, Citing Lack Of Funding, Other Reasons. The Scripps Howard/Kansas City infoZine examines how some medical clinics across the U.S. that specialize in treating patients with HIV are closing due to lack of funding and decreased demand, among other reasons.
Recent calls by California Gov. Arnold Schwarzenegger and others to study the legalization of marijuana as a way of boosting tax revenues are "irresponsible" and send a dangerous message, the chairman of the board of the drug abuse education program D.A.R.E., prominent Los Angeles attorney Louis "Skip" Miller, said today. "Marijuana is a dangerous drug with numerous demonstrable ill effects on health," Mr. Miller added.
Leading mental health advocates and political, medical and policy experts, including Mrs. Tipper Gore, George Stephanopoulos, Dr. Sanjay Gupta and Richard Gephardt, will address the changes and challenges ahead for the mental health field at Mental Health America"s Centennial Conference, June 10-13, in Washington, D.C.
A new report, issued by an expert committee convened by the AAMC (Association of American Medical Colleges) and the Howard Hughes Medical Institute (HHMI), for the first time defines scientific competencies for future medical school graduates and for undergraduate students who want to pursue a career in medicine.
Patients with symptoms of stroke or transient ischemic attack (TIA or brain attack) are missing out on potentially life saving treatment because they are routinely considered by the NHS as low priority cases. Instead of being fast-tracked into hospital for surgery the vast majority of patients are spending weeks and sometimes months on poorly managed referral pathways with the risk of going on to have more severe strokes.
Medtronic, Inc. (NYSE: MDT) announced results of a randomized, controlled trial to demonstrate the benefits of an insulin pump therapy augmented with real-time continuous glucose monitoring (Personal CGM) versus a conventional pump and self-monitoring of blood glucose in type 1 diabetes patients with poor metabolic control. Study findings showed that patients who used Personal CGM more than 70 percent of the time achieved nearly a full percentage point reduction in A1C (average blood glucose levels). The results were presented at the 69th Annual Scientific Sessions of the American Diabetes Association (ADA) in New Orleans.
The United Nations World Food Programme (WFP) is streaming
In an effort to foster global biomedical research that will ultimately lead to new and improved treatments for patients with blood diseases, the American Society of Hematology (ASH) and the European Hematology Association (EHA) have collaborated to create the Translational Research Training in Hematology (TRTH) program. This program will provide promising translational investigators an opportunity to undertake intensive training in the causes, diagnosis, and experimental treatment of hematologic disorders from some of the most recognized names in the field.
The BMA on Thursday welcomed the Health Select Committee"s call for the government to gather central information on the cost to the NHS of private management consultants.
UC Santa Barbara and Sansum Diabetes Research Institute scientists have demonstrated for the first time that an automated artificial pancreas system (APS) can safely and effectively maintain desired blood glucose levels in patients with type 1 diabetes. The clinical study results will be presented today in a late-breaking poster session(1) at the American Diabetes Association"s 69th Scientific Sessions in New Orleans.
New Phase II data presented at the American Diabetes Association 69th Scientific Sessions in New Orleans show that the investigational type 2 diabetes treatment Syncria(R) (albiglutide) significantly reduced blood glucose levels and provided weight loss across weekly, biweekly and monthly dosing. Reducing blood sugar is a key part of managing type 2 diabetes, a disease that affects over 250 million people worldwide.
I want to update Members on the swine flu outbreak and how preparations in Wales are proceeding.
A billboard campaign in New Orleans that seeks to raise awareness of HIV has sparked controversy as some residents consider the ads - which feature characters that represent specific sexually transmitted infections - offensive, WDSU.com reports. The campaign, run by St. John Faith Church, features a group of so-called "HIV prevention mobsters." The group, which has several billboards across the city, contends that the campaign is effective because there has been an increase in the number of people calling the church seeking information about HIV testing (WDSU.com, 6/5).
The Cincinnati Enquirer examined how the "success stories" of people living longer with HIV - such as that of former National Basketball Association player Earvin "Magic" Johnson - can "illustrate how well anti-HIV medications work and might be part of the reason the epidemic still rages." The article discussed the efficacy of antiretrovirals, their side effects and the consequences of not taking the medications (O"Farrell [1], Cincinnati Enquirer, 6/5). The Enquirer also featured an overview of the history and science of HIV (O"Farrell [2], Cincinnati Enquirer, 6/5).
Michigan"s Medicaid program is growing by as many as 15,000 people a month, but fewer physicians are accepting new patients insured by the program, which physicians say pays too little to cover their costs, the Associated Press reports. Meanwhile, the Michigan governor"s office announced an additional 4 percent cut last month, which "will lower payments across the board for hospitals, dentists and doctors who treat Medicaid patients." The article notes that in Michigan, the program currently insures a record 1.6 million residents.
The King"s Fund has announced a series of new initiatives and projects to take forward its work to improve health care.
The announcement of the establishment of a new Indigenous Health, Rural and
PLC Systems Inc. (OTC Bulletin Board: PLCSF), a company focused on innovative cardiac and vascular medical device-based technologies, announced that it will demonstrate its RenalGuard System(TM) at EuroPCR, the annual meeting of the European Association of Percutaneous Cardiovascular Interventions (EAPCI), May 19-22, 2009, in Barcelona, Spain. More than 11,000 clinicians and professionals are expected to attend this event.
Research led by a leading expert on the positive benefits of napping at the University of California, San Diego School of Medicine suggests that Rapid Eye Movement (REM) sleep enhances creative problem-solving. The findings may have important implications for how sleep, specifically REM sleep, fosters the formation of associative networks in the brain.
Radiologists, like professional pilots for example, depend on good vision as part of their occupation. However, radiologists unlike pilots are not required to undergo regular vision testing. A new study found that approximately 50% of radiologists surveyed indicated they don"t recall ever having their vision tested or it had been 24 months or longer since their last vision exam.
AdvanDx announced it received FDA 510(k) clearance for GBS PNA FISH(R) for detection of Streptococcus agalactiae, aka Group B Strep, from turbid Lim Broths inoculated with vaginal and rectal swabs obtained from pregnant women between 35 and 37 weeks gestation. The 90 minute molecular diagnostic test enables rapid and highly sensitive detection of Group B Strep from Lim Broths to help detect colonization in pregnant women.
According to a research abstract presented on June 8, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, television watching may be an important determinant of bedtime, and may contribute to chronic sleep debt.
Opal Events is proud to present our next exciting conference Drug Discovery Partnerships: Academia & Industrial Interactions , to be held at the Hyatt Regency in Boston on October 28-30, 2009.
Diabetes UK has released a short, gritty video called "Setting the record straight", to show schoolchildren and young people about Type 1 diabetes.
Martin Simon Hickman, a 49-year-old unlicensed and counterfeit medicines dealer, was sentenced to two years imprisonment at the Southwark Crown Court after pleading guilty to six counts of selling and supplying fake and unlicensed medicines, and money laundering to the sum of ÷£1.4m.
The GMC has announced the launch date of a milestone in medical regulation. From 16 November, all doctors will need a licence in order to practise medicine in the UK.
A breakthrough in the treatment of cancer and an unexpected finding about the life span of blood clotting cells have led Victorian scientist Dr Kylie Mason to be awarded the prestigious 2009 Premier"s Award for Public Health and Medical Research.
Study results presented for the first
- Nearly two thirds (59%) of the British public are neglecting
In the normal lung, the airways are lined by a balanced mixture of ciliated, secretory and neuroendocrine cells which perform functions as diverse as air humidification, detoxification, and clearance of environmental particles. This balance can be altered dramatically by faulty adaptation responses of the lung to cigarette smoke or allergens in patients with Chronic Obstructive Pulmonary Disease (COPD) and asthma.
New data presented at the EHA (European
Overweight individuals who ate a low-calorie, low-carbohydrate diet high in plant-based proteins for four weeks lost weight and experienced improvements in blood cholesterol levels and other heart disease risk factors, according to a report in the June 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. A high-carbohydrate, low-fat vegetarian diet also resulted in weight loss but without the additional cardiovascular benefits.
In this week"s edition of Proceedings of the National Academy of Sciences, PNAS, Uppsala University scientists describe a new mechanism behind an important process that causes a rapid reduction of DNA in the chromosomes of bacteria. The findings advance our knowledge of how DNA content has been reduced, which is something that has occurred in bacteria that live as parasites inside the cells of other organisms.
As many as fifteen million American women suffer from a disabling medical condition known as fibromyalgia. In the medical community, sides have been drawn over whether fibromyalgia is a genuine syndrome or a catchall diagnosis based on vague clinical criteria. In The Fibromyalgia Controversy, M. Clement Hall, MD presents an unbiased overview of the fibromyalgia situation today and reviews the most up-to-date opinions and studies on this condition and its surrounding controversy.
For car designers, secret agents in the movies and jet fighter pilots, data eyeglasses - also called head-mounted displays, or HMDs for short - are everyday objects. They transport the wearer into virtual worlds or provide the user with data from the real environment. At present these devices can only display information. "We want to make the eyeglasses bidirectional and interactive so that new areas of application can be opened up," says Dr. Michael Scholles, business unit manager at the Fraunhofer Institute for Photonic Microsystems IPMS in Dresden. A group of scientists at IPMS is working on a device which incorporates eye tracking - users can influence the content presented by moving their eyes or fixing on certain points in the image. Without having to use any other devices to enter instructions, the wearer can display new content, scroll through the menu or shift picture elements. Scholles believes that the bidirectional data eyeglasses will yield advantages wherever people need to consult additional information but do not have their hands free to operate a keyboard or mouse. The Dresden-based researchers have integrated their system"s eye tracker and image reproduction on a CMOS chip. This makes the HMDs small, light, easy to manufacture and inexpensive.
New research indicates that natural selection may shape the human genome
The UK"s longest established meningitis charity - the Meningitis Trust - is encouraging carers across the UK to speak out and earn the recognition that they deserve, as part of Carer"s Week (June 8 - 14).
Methuselah Foundation has identified Organovo, Inc. as a leader in the extraordinary science of bio-printing. The US Department of Health and Human Services predicts: "Within 20 years regenerative medicine will be the standard of care for replacing all tissue/organ systems in the body." Organovo, with the support of Methuselah Foundation, is applying its breakthrough organ printing technologies to make that prediction a reality.
Roche announced it will start Phase III clinical investigations for aleglitazar, its innovative PPAR co-agonist R1439 which is uniquely designed to reduce cardiovascular morbidity and mortality in high risk patients with type 2 diabetes. This decision is supported by data from the Phase II SYNCHRONY study published today in The Lancet(1) and announced at the American Diabetes Association meeting in New Orleans. The Phase III program is anticipated to start in the second half of 2009.
DOR BioPharma, Inc. (DOR or the Company) (OTC Bulletin Board: DORB), a late-stage biopharmaceutical company, announced that it has received Protocol Assistance feedback from the European Medicines Agency (EMEA) on the design of its confirmatory, pivotal, Phase 3 clinical trial evaluating its lead product orBec(R) for the treatment of acute gastrointestinal Graft-versus-Host Disease (GI GVHD).
Pharmasset, Inc. (Nasdaq: VRUS) announced that it had completed the single ascending dose study and begun dosing in a multiple ascending dose trial with PSI-7851, a nucleotide analog polymerase inhibitor for the treatment of chronic hepatitis C virus (HCV) infection. This study is designed to assess the safety, tolerability and antiviral activity of PSI-7851 over 3 days in HCV-infected individuals.
A Brown University professor is among the first in the country to win a federal research grant funded by national economic stimulus efforts.
Mental Health America, celebrating its 100th Anniversary as the founder of the organized mental health movement, will honor Senators Edward M. Kennedy and Pete Domenici for their legendary work on behalf of individuals with mental health conditions at its Centennial Gala on Thursday, June 11, in Washington, D.C.
The WHO and UNICEF on Tuesday said that vitamin A supplements and deworming tablets are safe, after two deaths and the "sickness of hundreds" were alleged among the children who received the interventions during a nationwide campaign in Bangladesh, Bernama.com reports (Bernama.com, 6/9).
In the White House"s pitches for health care reform, controlling costs has replaced universal coverage as the leading imperative to overhaul the system. A top White House economist, Christina Romer, said in a public appearance Monday, "Good health care reform is good economic policy," the San Francisco Chronicle reports. "Fixing what"s wrong with our health care system is no longer a luxury we hope to achieve - it"s a necessity we cannot postpone any longer" (Abate, 6/9).
The word constipation comes from the Latin constipare meaning "to press, crowd together", and from 1400 A.D. Latin Constipationem. According to Medilexicon"s medical dictionary, constipation is "A condition in which bowel movements are infrequent or incomplete". Constipation is also known as costiveness, and irregularity.
A New York City law that will go into effect in July could make it easier for antiabortion-rights protesters to be arrested for restricting access to abortion clinics or harassing people trying to enter the facilities, the New York Times reports. Current law allows authorities to make arrests only if the person directly affected, such as a woman entering a clinic, is willing to press charges. However, the new law would allow third parties, such as clinic workers, to press charges if they witnessed the activity, the Times reports. New York City"s Dr. Emily"s Women"s Health Center and NARAL Pro-Choice New York spearheaded efforts to pass the legislation in response to antiabortion-rights demonstrators who target women on their way to clinics and attempt to persuade them to carry their pregnancies to term. Clinic workers report that the protesters also have harassed women as they left the subway or surrounded them as they walked to the clinic. New York City Mayor Michael Bloomberg signed the law in April. Joan Malin, president and CEO of Planned Parenthood of New York City, said the group is "not against people demonstrating. But there is a line between freedom of speech and harassment and bullying" (Bosman, New York Times, 6/6).
Body chemistry changes that lead to Type 2 diabetes begin several years before symptoms become apparent, according to new research.
The Royal College of Pathologists welcomes the Royal College of Physicians" report into the future
Children who are bullied at school are up to four times more likely than their peers to develop psychotic symptoms, such as hallucinations, delusions and paranoia - and the more severe the bullying the more severe the symptoms.
UroToday.com - At present, no consensus exists on how patients with PSA recurrence after radical prostatectomy (RP) should be treated. Although patients with postoperative PSA recurrence frequently undergo androgen deprivation therapy (ADT) before evidence of metastatic disease, the benefit of this approach is uncertain. As no randomized studies are performed in this clinical setting there is no conclusive evidence that hormone therapy (HT) after RP will prolong survival or reduce morbidity.
The findings of two 52-week studies show that the investigational ultra rapid acting insulin AFRESA® (insulin human [rDNA origin]) Inhalation Powder combined with basal insulin is comparable to standard of care therapies in controlling post-meal blood sugar levels, and also results in significantly less weight gain and risk of hypoglycemia for adult patients with diabetes. The data were presented at the American Diabetes Association"s 69th Scientific Sessions.
According to a research abstract that will be presented on Wednesday, June 10, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, getting more high-quality sleep is associated with better academic performance. The positive relationship is especially relevant to performance in math.
In places where young women outnumber young men, research shows the hemlines rise but the marriage rates don"t because the young men feel less pressure to settle down as more women compete for their affections.
The New York Times on Friday examined how two events -- controversy surrounding President Obama"s upcoming commencement speech at University of Notre Dame on Sunday and the selection of a replacement for retiring Supreme Court Justice David Souter -- are testing the "delicate balancing act" the president has pursued on abortion rights. Notre Dame"s invitation to Obama to deliver the commencement speech and receive an honorary degree has sparked ongoing protests from abortion-rights opponents, and Obama is now forced to decide whether he will recognize this opposition in his address on Sunday. According to Anita Dunn, the president"s communication adviser, Obama likely will "make reference to the controversy" in his speech but will not "allow it to become the focus of a day that"s actually supposed to be about the graduates." Meanwhile, the pending Supreme Court vacancy has "galvanized backers of abortion rights," according to the Times. Although both sides expect that Obama will select a nominee who supports abortion rights, advocates "are taking no chances," the Times reports.Obama has attempted to present a nuanced approach to abortion-rights issues and expressed that he intends to form consensus around reducing unintended pregnancies and promoting adoption. In addition, his policy moves to date have attempted "to straddle the abortion divide" by creating a dialogue with religious conservatives, avoiding contentious legislative fights and taking a gradual approach to reversing the policies of former President George W. Bush, the Times reports. Obama has named abortion-rights supporters to head jobs, such as his nomination of Dawn Johnsen, a former legal director of NARAL Pro-Choice America, to lead the Justice Department"s Office of Legal Counsel. He also repealed the "Mexico City" policy, which prohibited federal funding for international groups that provide abortion services or information; lifted some limits on embryonic stem cell research; proposed decreasing funding for abstinence-only sex education; and took action to rescind the Bush administration"s HHS provider "conscience" rule allowing health care workers to refuse to provide services they find morally or religiously objectionable. However, the president has stepped away from some abortion-related issues, including the Freedom of Choice Act, which would effectively codify Roe v. Wade. Although Obama said in a 2007 speech to Planned Parenthood that he would sign the bill if elected president, he said in a press conference last month that it is not his "highest legislative priority."Meanwhile, Obama"s top domestic policy adviser, Melody Barnes, is convening a series of meetings with leaders from both sides of the abortion rights debate to discuss policy ideas, with an aim of drafting recommendations by late summer. David Gushee, a Christian ethics professor at Mercer University who has participated in the talks, said the president is signaling to moderate Catholics and evangelicals that "he clearly knows what the bright red lines are and is trying to avoid stepping over them." However, some religious conservatives and abortion-rights opponents who have not been included in the discussions contend that "Obama is trying to have it both ways," according to the Times. Charmaine Yoest, president of Americans United for Life, said coming to a consensus would entail the president advocating for restrictions such as parental consent requirements for minors and bans on certain abortion procedures. Sen. Sam Brownback (R-Kan.), who opposes abortion rights, called Obama"s strategy "[m]oderate rhetoric, hard-left policies."Polls show that U.S. residents remain "deeply conflicted" over abortion rights, with support declining over the years, the Times reports. About 60% of U.S. residents believed abortion should be legal in all or most cases in a 1995 poll; a recent Pew Research Center poll showed the number declined to 46% (Stolberg, New York Times, 5/15).
A new study finds colorectal cancer incidence rates for both males and females increased in 27 of 51 countries worldwide between 1983 and 2002, and points to increasing Westernization as being a likely culprit. The rise was seen primarily in economically transitioning countries including Eastern European countries, most parts of Asia, and some countries of South America. The study is the first in a peer-reviewed journal to present colorectal cancer incidence trends across all five continents. It appears in the June 2009 issue of Cancer Epidemiology Biomarkers and Prevention. An accompanying editorial says the rise points toward a failed early detection and prevention strategy as well as failure to address lifestyle and dietary challenges of urbanization that affect most of the globe.
Cancer patients who are older than 65 years have poorer physical health and, in some cases, mental health when compared with people of the same age group without cancer, according to a study in the June 9 online issue of the Journal of the National Cancer Institute.
Self-reported nightmares among patients seeking emergency psychiatric evaluation uniquely predicted elevated suicidal symptoms, according to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.
Dehydration (from the Greek hydor (water)) and the Latin prefix de- (indicating deprivation, removal, and separation) occurs when more water and fluids are exiting the body than are entering the body. With about 75% of the body made up of water found inside cells, within blood vessels, and between cells, survival requires a rather sophisticated water management system. Luckily, our bodies have such a system, and our thirst mechanism tells us when we need to increase fluid intake. Although water is lost constantly throughout the day as we breathe, sweat, urinate, and defecate, we can replenish the water in our body by drinking fluids. The body can also shift water around to areas where it is more needed if dehydration begins to occur.
Bicuspid Aortic Valve (BAV), a condition in which patients" aortic valves have just two leaflets instead of the normal three, is the most common cardiac anomaly, affecting up to two percent of the general population. The defect can result in calcification deposits on the heart valve, leakage of the valve and may results in a feeling of tightness in the chest as well as shortness of breath. The condition is easily diagnosed; often physicians can hear a "click" or a murmur when they listen to a BAV patient"s heart with a stethoscope.
Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. Recent research has found that the expression of hepatic TRB3 increased in a rat model of diabetes. TRB3 could block the insulin signaling pathway through inhibiting Akt activation, which contributes to insulin resistance.
So many classic childhood movies (Dumbo) and sing-a-longs (Do your ears hang low? Do they wobble to and fro?) emphasize large and protruding ears. But it turns out that having protruding ears is often-times a humiliating feature for a teenager.
Restaurants in Germany legally sell alcohol to teenagers after their sixteenth birthdays and French children drink wine with dinner at an early age, but U.S. parents who follow this relaxed European example, believing it fosters a healthier attitude toward alcohol, should be careful -- it may increase the likelihood that their children binge drink in college.
The virus that causes winter vomiting disease invades cells by attaching to particular sugar molecules on the surface of the cells. This is the conclusion of a thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden. This result may be an important step in the development of a drug against the regular hospital-based epidemics caused by the virus.
The chemical bisphenol A, commonly found in many plastic household items, has been linked to yet another health problem in animals - an increased frequency of arrhythmias, or heartbeat irregularities, a new study found. The results, seen only in females, will be presented Saturday at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
The European Parkinson"s Disease Association (EPDA) announces
The United States is becoming a nation of haves and have-nots when it comes to tobacco control, according to a comprehensive publication on cigarette smoking prevalence and policies in the U.S. which has just been released.
Researchers trying to uncover why premature birth is a growing problem in the United States and one that disproportionately affects black women have found that pre-pregnancy depressive mood appears to be a risk factor in preterm birth among both blacks and whites.
Osteoarthritis is commonly diagnosed in the late and irreversible stages, when treatment can only be expected to decrease pain and slow progression of disease. Because osteoarthritis is a widespread problem in dogs, horses and humans, doctors and veterinarians need a precise way to diagnose the disease early and accurately. Now, University of Missouri researchers are investigating potential biomarkers in dogs for early diagnosis of osteoarthritis, which could help identify patients at increased risk of developing osteoarthritis.
Ziehm Imaging is proud to announce that the United States Food and Drug Administration (FDA) has given 510k clearance for the latest innovative mobile C-arm from Ziehm Imaging, the Ziehm Vision(R) RFD, for marketing and sales within the United States. Designed for use in endovascular surgery, interventional cardiology and interventional radiology, the Ziehm Vision RFD mobile C-arm combines the latest flat-panel technology and a true fully digital imaging chain with a compact design that delivers exceptional image quality. During demanding procedures physicians will benefit from improved visualization, workflow and reduced radiation dose.
Black women in Washington, D.C., have higher rates of AIDS and other chronic health conditions such as obesity, diabetes and heart disease than women of other races, according to a study released today by the Kaiser Family Foundation, the Washington Post reports. According to the study - which is based on CDC and federal population data - the incidence of AIDS cases for black women is 176 per 100,000, higher than that of any other group of women in the district. Lack of education, poverty, unemployment, stress, and inadequate living conditions and health care coverage contribute to black women"s poorer health, the study finds (Fears, Washington Post, 6/10).
Senators will likely pay for at least a portion of the expected $1 trillion-plus health reform price tag by taxing employer-provided health benefits that are significantly more expensive than the basic plan for federal employees, which costs $13,000 a year for a family, the Washington Post reports. A new tax on the benefits, which are now exempt, is "perhaps the best way to raise money for an overhaul of the health care system," Sen. Baucus, D-Mont., the chairman of the Senate Finance Committee, which must find a way to pay for the bill, told reporters (Montgomery, 6/10).
Medtronic, Inc (NYSE: MDT) announced the launch of the Shock-Less clinical trial. This trial will identify ways physicians can improve the quality of care for patients through optimal application of device-based tools designed to reduce unnecessary shocks in patients with implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy-defibrillator (CRT-D) devices. Specifically, the Shock-Less study aims to create evidence that will increase the use of programming tools that reduce unnecessary shocks including features on Medtronic devices, such as Medtronic"s exclusive Lead Integrity Alert™ (LIA) and Anti-Tachycardia Pacing (ATP) During Charging™.
An analysis of previous studies indicates that allogeneic stem cell transplantation (SCT) (stem cells from a compatible donor) is associated with significant overall and relapse-free survival benefit among adult patients with intermediate- and poor-risk but not good-risk acute myeloid leukemia in first complete remission, compared with nonallogeneic SCT therapies, according to an article in the June 10 issue of JAMA.
Cancer patients who are older than 65 years have poorer physical health and, in some cases, mental health when compared with people of the same age group without cancer, according to a study in the June 9 online issue of the Journal of the National Cancer Institute.
Jason Karlawish, M.D., associate professor of medicine, University of Pennsylvania, will share the latest information on Alzheimer"s disease at a community lecture at 1 p.m., Wednesday, June 10 at Rodef Shalom Congregation, 4905 Fifth Ave., Shadyside. The event is free and open to the public.
Commenting on the publication of the NHS Confederation report Dealing with the downturn: the greatest ever leadership challenge for the NHS, Dr Peter Carter, Chief Executive & General Secretary of the Royal College of Nursing (RCN), said:
Metoclopramide, a drug approved in the U.S. for nausea, vomiting and heartburn poses no significant risks for the fetus according to a large cohort study published in the June 11 issue of the prestigious New England Journal of Medicine, "The Safety of Metoclopramide Use in the First Trimester of Pregnancy" (N Engl J Med 2009;360:24 June 11, 2009).
New Jersey state Sen. Joseph Vitale (D) -- chair of the Senate Health, Human Services and Senior Citizens Committee -- earlier this week proposed a plan to temporarily reduce rebate checks to senior citizens earning $100,000 to $150,000 in an effort to alleviate the effects of possible budget cuts on certain populations, the Newark Star-Ledger reports. Vitale"s proposal also would avert planned $6 to $15 prescription drug copayments for people living with HIV/AIDS in the state (Livio, Newark Star-Ledger, 5/12). The copayments are part of Gov. Jon Corzine"s (D) $29.8 billion spending proposal for the state"s new fiscal year and would collect $1.36 million by creating copayments for HIV/AIDS drugs based on a sliding scale determined by income. The copayments would affect 9,000 people living with HIV/AIDS who have obtained no-cost medicine from the state because they do not qualify for other assistance programs. Advocates said that the copayments will hurt patients who are already struggling because of the poor economy (Kaiser Daily HIV/AIDS Report, 4/23). According to the Star-Ledger, Vitale"s proposal would save the state $15.7 million, including $9.7 million needed to allow 17,000 low-income families to enroll in the state"s health insurance program, FamilyCare. Senate Budget Committee Chair Barbara Buono (D) said that she does not believe it is possible to restore program cuts "given the collapse of revenues." According to the Office of Legislative Services, the current deficit for this year"s budget, which ends June 30, is at least $1.2 billon. Vitale said, "Our convictions are going to be tested as we come to terms with the fact that we simply don"t have enough money to fund all of the state"s priorities." He added, "But unless funding is restored for programs like NJ FamilyCare, Medicaid drug benefits and the AIDS Drug Distribution Program, I will be voting against the" fiscal year 2010 budget (Newark Star-Ledger, 5/12).
Thailand"s Office of Welfare Promotion, Protection and Empowerment of Vulnerable People earlier this week held a public hearing to discuss various risks facing the country"s children, including HIV/AIDS, Thailand"s The Nation reports. The office plans to present a draft report on the state of child rights in the country. The report will be sent through the Foreign Affairs Ministry to the United Nations" Convention on the Rights of the Child in July, according to ministry deputy director Saran Samarnphan. Young people were among some of the attendees at the public hearing, according to The Nation.Youth representative Natkamon Tumpaeng said that the government has not provided adequate sex education to young people, which has resulted in unwanted pregnancies and the spread of HIV. He said, "Without sex education, many youths have clearly engaged in unsafe sex." Passacha Pachuen, a public relations official for a council on children and youth in the Surin province, said that at many schools, teachers are forcing sex on students. "Many teachers demand sex or other favors from their students in exchange for good grades," Passacha said. In addition, Amnat Siangsawas, the deputy chair of the council of youth and children in the city of Nakhon Sawan, said that a lack of res often leads many children into the labor market, where they are being exploited. Amnat added that officials should "put in place mechanisms that will help them" (The Nation, 5/13).
One of the most widely read books in endocrinology recently came out in its second edition.
The World Health Organisation (WHO) and European Federation of Allergy and Airways Diseases (EFA) today announced that they are bringing together over 150 international delegates to discuss the growing epidemic of Chronic Respiratory Diseases (CRD) that affects one billion people worldwide1, [2], [3] and is responsible for four million deaths annually1. The conference which will discuss the implementation of a five-year initiative to unite policy makers, providers and patient groups will be hosted by the Italian Ministry of Health in Rome on June 12 and 13.
Cegedim Dendrite announced the launch of COUNTERxFEIT DETECT, a new offering that will assist pharmaceutical companies in identifying counterfeit product and determining where it entered their United States supply chains. Cegedim Dendrite is the leading provider of compliance technology solutions and services in the pharmaceutical industry.
Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including red blood cells, bone, and muscle, today announced it will provide three oral presentations on data from its ACE-031 program at the Endocrine Society"s 91st Annual Meeting to be held in Washington, DC from June 10-13, 2009. The presentations will provide results from preclinical studies highlighting the effects of its lead investigational product for treating diseases involving the loss of muscle mass and function.
Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. In gastric cancer, CHFR promoter hypermethylation has been reported to lead to chromosome instability (CIN) and genetic instability is one of the hallmarks of human cancer.
The value and cost-effectiveness of screening for left ventricular (LV) dysfunction remains unclear, particularly since specific, evidence-based treatments are not available for the majority of patients with preserved systolic dysfunction, reports a study in the June issue of the Journal of Cardiac Failure, published by Elsevier.
The Group of Eight (G8) industrial nations are "collectively off course in delivering on a 2005 pact to more than double aid to Africa through 2010," according to an annual report released Thursday by the One Campaign, Reuters/Washington Post reports (Wroughton, Reuters/Washington Post, 6/11).